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41.
The major locus for multifactorial nonsyndromic cleft lip maps to mouse Chromosome 11 总被引:4,自引:0,他引:4
Cleft lip with or without cleft palate, CL(P), a common human birth defect, has a genetically complex etiology. An animal model with a similarly complex genetic basis is established in the A/WySn mouse strain, in which 20% of newborn have CL(P). Using a newly created congenic strain, AEJ.A, and SSLP markers, we have mapped a major CL(P)-causing gene derived from the A/WySn strain. This locus, here named clf1 (cleft lip) maps to Chromosome (Chr) 11 to a region having linkage homology with human 17q21-24, supporting reports of association of human CL(P) with the retinoic acid receptor alpha (RARA) locus. 相似文献
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CLARE D. FITZGIBBON 《Mammal Review》1995,25(1-2):19-30
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Purification and properties of the endocellular β-glucosidase of Candida cacaoi Buckley and Van Uden CBS 2020 总被引:1,自引:1,他引:0
D. Drider P. Pommares P. Chemardin A. Arnaud P. Galzy 《Journal of applied microbiology》1993,74(4):473-479
D. DRIDER, P. POMMARES, P. CHEMARDIN, A. ARNAUD AND P. GALZY. 1993. The endocellular enzyme β-glucosidase of Candida cacaoi was purified by ion-exchange chromatography and gel filtration. The molecular weight was 220 ± 10 kDa; its optimum pH was between 4 and 5.5 and its optimum temperature was 60C. This enzyme was active against soluble glucosides tested with β(1–2), β(1–3), β(1–4) and even α(1–4) and α(1–6) and was inhibited by D-glucono-δ-lactone. The enzyme was constitutive but its synthesis was repressed by glucose. 相似文献
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Freshwater crayfish are key members of aquatic communities due to their large size and abundance. Although most commonly regarded
as herbivores and detritivores, they are also selective predators. The crayfish plague fungus Aphanomyces astaci (Schikora) led to the elimination of a stock of white-clawed crayfish, Austropotamobius pallipes (Lereboullet) from Lough Lene, Co. Westmeath, in 1987. Samples taken of the flora and benthic communities of two Irish lakes,
one (Lough Bane) formerly containing crayfish and the other (Lough Lene) immediately following a plague outbreak, were compared
to similar samples taken a year later and ecological shifts were noted and compared to laboratory feeding results. Over time,
Chara strands increased in mean length, and molluscs became more abundant. 相似文献